Synthesis of [11C]bexarotene by cu-mediated [ 11C]carbon dioxide fixation and preliminary PET imaging

DOI: 10.1021/ml500065q

Source and publish data:

ACS Medicinal Chemistry Letters p. 668 - 672 (2014)

Update date:2022-08-03

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Authors:

Rotstein, Benjamin H.

Hooker, Jacob M.

Woo, Jiyeon

Collier, Thomas Lee

Brady, Thomas J.

Liang, Steven H.

Vasdev, Neil

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Article abstract of DOI:10.1021/ml500065q

Bexarotene (Targretin) is a retinoid X receptor (RXR) agonist that has applications for treatment of T cell lymphoma and proposed mechanisms of action in Alzheimer's disease that have been the subject of recent controversy. Carbon-11 labeled bexarotene ([

Full text of DOI:10.1021/ml500065q

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