A New Method for the Synthesis of Nε-Acetyl-Nε-hydroxy-L-lysine, the Iron-Binding Constituent of Several Important Siderophores

DOI: 10.1021/jo00096a030

Source and publish data:

Journal of Organic Chemistry p. 4858 - 4861 (1994)

Update date:2022-09-26

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Authors:

Hu, Jingdan

Miller, Marvin J.

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Article abstract of DOI:10.1021/jo00096a030

Oxidation of the ε-amino group of N^α-(carbobenzyloxy)-L-lysine methyl ester with dimethyldioxirane in acetone gave the acetone-derived nitrone of the desired hydroxylamine.Acidic hydrolysis, acetylation, and subsequent deprotection provided a s

Full text of DOI:10.1021/jo00096a030

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