Journal of Organic Chemistry p. 4943 - 4949 (1994)
Update date:2022-08-03
Topics:
Boger
Nishi
Teegarden
The synthesis and preliminary evaluation of 10 and 11, stable precursors to the inherently reactive but isolable p-quinonemethide analog 9 of the CC-1065 and duocarmycin alkylation subunits, are detailed. The p-quinonemethide 9, while reactive (t( 1/2 ) <
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