p-Quinomethide analog of the CC-1065 and duocarmycin alkylation subunits

DOI: 10.1021/jo00096a043

Source and publish data:

Journal of Organic Chemistry p. 4943 - 4949 (1994)

Update date:2022-08-03

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Authors:

Boger Boger

Nishi Nishi

Teegarden

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Article abstract of DOI:10.1021/jo00096a043

The synthesis and preliminary evaluation of 10 and 11, stable precursors to the inherently reactive but isolable p-quinonemethide analog 9 of the CC-1065 and duocarmycin alkylation subunits, are detailed. The p-quinonemethide 9, while reactive (t( 1/2 ) <

Full text of DOI:10.1021/jo00096a043

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