Convenient Method for the Preparation of Some Polyhydroxamic Acids: Michael Addition of Amines to Acrylohydroxamic Acid Derivatives

DOI: 10.1016/S0040-4039(00)77052-3

Source and publish data:

Tetrahedron Letters p. 5157 - 5160 (1994)

Update date:2022-08-04

Topics:

Authors:

Koshti, Nirmal M.

Jacobs, Hollie K.

Martin, Patrick A.

Smith, Paul H.

Gopalan, Aravamudan S.

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Article abstract of DOI:10.1016/S0040-4039(00)77052-3

Reagents 1, 2, and 3 are readily prepared by the reaction of the appropriate hydroxylamine derivatives with acryloyl chloride.They undergo Michael addition with a variety of amines to give the corresponding O-protected hydroxamate derivatives in moderate

Full text of DOI:10.1016/S0040-4039(00)77052-3

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