Synthesis of new aminocyclitols as potent enzymatic inhibitors

Article abstract of DOI:10.1016/S0040-4039(00)60726-8

The syntheses of new pseudo-saccharides having an allylic amino moiety or an aziridine group are reported starting from methyl-α-D-glucopyranoside. To enhance the hydrophilic/lipophilic balance, pseudo-saccharides 9 and 10 were linked with a glycosyl deri