Chemistry - A European Journal (2020)
Update date:2022-07-29
Topics:
Baumann, Andreas N.
Dechent, Jonas
Didier, Dorian
Jagau, Thomas C.
Müller, Nicolas
Music, Arif
Conventional methods carrying out C(sp2)?C(sp2) bond formations are typically mediated by transition-metal-based catalysts. Herein, we conceptualize a complementary avenue to access such bonds by exploiting the potential of electrochemistry in combination with organoboron chemistry. We demonstrate a transition metal catalyst-free electrocoupling between (hetero)aryls and alkenes through readily available alkenyl-tri(hetero)aryl borate salts (ATBs) in a stereoconvergent fashion. This unprecedented transformation was investigated theoretically and experimentally and led to a library of functionalized alkenes. The concept was then carried further and applied to the synthesis of the natural product pinosylvin and the derivatization of the steroidal dehydroepiandrosterone (DHEA) scaffold.
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Doi:10.1021/om500140g
(2014)Doi:10.1016/j.tet.2012.06.083
(2012)Doi:10.1002/cbdv.201900597
(2020)Doi:10.1016/S0040-4039(00)73136-4
(1994)Doi:10.1016/j.catcom.2019.105889
(2020)Doi:10.1016/S0040-4039(00)73429-0
(1994)