Glutathione-S-transferase activates novel alkylating agents

DOI: 10.1021/jm00036a016

Source and publish data:

Journal of Medicinal Chemistry p. 1501 - 1507 (1994)

Update date:2022-07-30

Topics:

Authors:

Lyttle Lyttle

Satyam Satyam

Hocker Hocker

Bauer Bauer

Caldwell

Hui Hui

Morgan Morgan

Mergia Mergia

Kauvar Kauvar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00036a016

Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta

Full text of DOI:10.1021/jm00036a016

Products guided by the article

Product name:2-<(p-tolylsulfonyl)oxy>ethyl N,N,N',N'-tetraethylphosphorodiamidate

Cas No:158382-40-2

R&D Labs maybe for 158382-40-2

Sdow

website:http://www.sdowchem.com

Contact:86-135-2193 7483

Address:8-106 taiyue building
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
Hebei Jiangkai import and export trade Co., Ltd.

Contact:15633024714

Address:hebei shijiazhuang
Shanghai UCHEM Inc.

Contact:+86-21-56338808

Address:799 Dunhuang Road, Putuo
SHANGHAI T&W PHARMACEUTICAL CO., LTD.

website:http://www.trustwe.com

Contact:+86-21-61551611

Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong

Relevant to this article

Doi:10.1021/ja01161a514
(1950)
PPL-catalyzed enzymatic asymmetrization of a 2-substituted prochiral 1,3-diol with remote chiral functionality: Improvements toward synthesis of the eutomers of SCH 45012

Doi:10.1016/0040-4039(94)88071-9
(1994)
Catalyst-free thiol-yne click polymerization: A powerful and facile tool for preparation of functional poly(vinylene sulfide)s

Doi:10.1021/ma402559a
(2014)
Control of regio- and enantioselectivity in the asymmetric organocatalytic addition of acetone to 4-(trifluoromethyl)pyrimidin-2(1H)-ones

Doi:10.1002/ejoc.201301542
(2014)
Rapid synthesis of alkoxyamine hydrochloride derivatives from alkyl bromide and N,N′-Di-tert-butoxycarbonylhydroxylamine [(Boc)₂NOH]

Doi:10.1080/00397911.2014.895014
(2014)
Synthesis of half-sandwich iron carboxyalkyls and iron (thiocarboxy)alkyls: Reaction of cyclopentadienyldicarbonyliodoiron with O- and S-based nucleophiles in the presence of triphenylphosphine

Doi:10.1021/om00008a048
(1995)

Article Doi