Glutathione-S-transferase activates novel alkylating agents

DOI: 10.1021/jm00036a016

Source and publish data:

Journal of Medicinal Chemistry p. 1501 - 1507 (1994)

Update date:2022-07-30

Topics:

Authors:

Lyttle Lyttle

Satyam Satyam

Hocker Hocker

Bauer Bauer

Caldwell

Hui Hui

Morgan Morgan

Mergia Mergia

Kauvar Kauvar

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Article abstract of DOI:10.1021/jm00036a016

Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta

Full text of DOI:10.1021/jm00036a016

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Product name:2-<(p-tolylsulfonyl)oxy>ethyl N,N,N',N'-tetraethylphosphorodiamidate

Cas No:158382-40-2

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