Glutathione-S-transferase activates novel alkylating agents

DOI: 10.1021/jm00036a016

Source and publish data:

Journal of Medicinal Chemistry p. 1501 - 1507 (1994)

Update date:2022-07-30

Topics:

Authors:

Lyttle Lyttle

Satyam Satyam

Hocker Hocker

Bauer Bauer

Caldwell

Hui Hui

Morgan Morgan

Mergia Mergia

Kauvar Kauvar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00036a016

Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta

Full text of DOI:10.1021/jm00036a016

Products guided by the article

Product name:2-<(p-tolylsulfonyl)oxy>ethyl N,N,N',N'-tetraethylphosphorodiamidate

Cas No:158382-40-2

R&D Labs maybe for 158382-40-2

Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Sichuan WeiKeqi Biological Technology Co., Ltd.

website:https://www.weikeqi-biotech.com/en

Contact:86-028-81700200

Address:sichuan Chengdu Qingjiang Zhonglu 63号
Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Yancheng Creator Chemical Co., Ltd

Contact:0086-515-88710008 88710068 88710858 88710868

Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City

Relevant to this article

Doi:10.1021/ja01161a514
(1950)
PPL-catalyzed enzymatic asymmetrization of a 2-substituted prochiral 1,3-diol with remote chiral functionality: Improvements toward synthesis of the eutomers of SCH 45012

Doi:10.1016/0040-4039(94)88071-9
(1994)
Catalyst-free thiol-yne click polymerization: A powerful and facile tool for preparation of functional poly(vinylene sulfide)s

Doi:10.1021/ma402559a
(2014)
Control of regio- and enantioselectivity in the asymmetric organocatalytic addition of acetone to 4-(trifluoromethyl)pyrimidin-2(1H)-ones

Doi:10.1002/ejoc.201301542
(2014)
Rapid synthesis of alkoxyamine hydrochloride derivatives from alkyl bromide and N,N′-Di-tert-butoxycarbonylhydroxylamine [(Boc)₂NOH]

Doi:10.1080/00397911.2014.895014
(2014)
Synthesis of half-sandwich iron carboxyalkyls and iron (thiocarboxy)alkyls: Reaction of cyclopentadienyldicarbonyliodoiron with O- and S-based nucleophiles in the presence of triphenylphosphine

Doi:10.1021/om00008a048
(1995)

Article Doi