Glutathione-S-transferase activates novel alkylating agents

DOI: 10.1021/jm00036a016

Source and publish data:

Journal of Medicinal Chemistry p. 1501 - 1507 (1994)

Update date:2022-07-30

Topics:

Authors:

Lyttle Lyttle

Satyam Satyam

Hocker Hocker

Bauer Bauer

Caldwell

Hui Hui

Morgan Morgan

Mergia Mergia

Kauvar Kauvar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00036a016

Alkylating agents which are activated by glutathione-S-transferases (GSTs) have been designed and synthesized. The model compound γ-glutamyl-α-amino- β-[(2-ethyl N,N,N',N'-tetraethyl- phosphorodiamidate)sulfonyl]propionylglycine (1) and the nitrogen musta

Full text of DOI:10.1021/jm00036a016

Products guided by the article

Product name:2-<(p-tolylsulfonyl)oxy>ethyl N,N,N',N'-tetraethylphosphorodiamidate

Cas No:158382-40-2

R&D Labs maybe for 158382-40-2

KA-SHING Business Trade Macau Co., Ltd.

Contact:00853-28430045

Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
Yingkou Sanzheng Organic Chemical Co. Ltd.

Contact:+86-417-3638818

Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu
Hangzhou Zhenghan Biological Technology Co., Ltd.

Contact:86-571-88781753

Address:liangzhu yuhang hangzhou city
Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0

Relevant to this article

Doi:10.1021/ja01161a514
(1950)
PPL-catalyzed enzymatic asymmetrization of a 2-substituted prochiral 1,3-diol with remote chiral functionality: Improvements toward synthesis of the eutomers of SCH 45012

Doi:10.1016/0040-4039(94)88071-9
(1994)
Catalyst-free thiol-yne click polymerization: A powerful and facile tool for preparation of functional poly(vinylene sulfide)s

Doi:10.1021/ma402559a
(2014)
Control of regio- and enantioselectivity in the asymmetric organocatalytic addition of acetone to 4-(trifluoromethyl)pyrimidin-2(1H)-ones

Doi:10.1002/ejoc.201301542
(2014)
Rapid synthesis of alkoxyamine hydrochloride derivatives from alkyl bromide and N,N′-Di-tert-butoxycarbonylhydroxylamine [(Boc)₂NOH]

Doi:10.1080/00397911.2014.895014
(2014)
Synthesis of half-sandwich iron carboxyalkyls and iron (thiocarboxy)alkyls: Reaction of cyclopentadienyldicarbonyliodoiron with O- and S-based nucleophiles in the presence of triphenylphosphine

Doi:10.1021/om00008a048
(1995)

Article Doi