Synthesis of a 125I labelled azido-substituted glibenclamide analogue for photoaffinity labelling of the sulfonylurea

Article abstract of DOI:10.1002/jlcr.2580340713

N-[4-(2-{4-Azido-2-hydroxy-5-[¹²⁵I]iodobenzamido}ethyl) benzenesulfonyl]-N'-cyclohexylurea has been prepared as a novel photoaffinity ligand for the sulfonylurea receptor. This involved synthesis of a 4-azidosalicyloyl analogue of glibenclamide