A Comparative Molecular Field Analysis Model for 6-Arylpyrrolobenzothiazepines Binding Selectively to the Mitochondrial Benzodiazepine Receptor

Article abstract of DOI:10.1021/jm00050a007

A series of 42 6-arylpyrrolo<2,1-d><1,5>benzothiazepines, which we have recently described as selective ligands of the mitochondrial benzodiazepine receptor (MBR) (Fiorini I.; et al.J.Med.Chem. 1994, 37, 1427-1438), have been investigated using the compar