Cyanocuprate-Mediated Intramolecular Biaryl Couplings Applied to an Ellagitannin. Synthesis of (+)-O-Permethyltellimagrandin II

Article abstract of DOI:10.1016/S0040-4039(00)77248-0

Generation of an intramolecularly tethered, nonracemic diaryl cuprate followed by its oxidation with ground state oxygen at -78 deg leads to a biaryl precursor to an ellagitannin.Subsequent attachment of the appropriate glucose unit completes the synthesi