European Journal of Medicinal Chemistry p. 127 - 131 (1994)
Update date:2022-07-30
Topics: Synthesis
Todoulou
Papadaki-Valiraki
Filippatos
Ikeda
De Clercq
A series of new N,N'-disubstituted thioureas were prepared and evaluated in vitro for their activity against myxoviruses. Compound N-[4-(3-propoxy-1H-1,2,4-triazol-1-yl)phenyl]-N'-(2-pyrazinyl)thiourea 5d exhibited specific activity against respiratory sy
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