Synthesis and anti-myxovirus activity of some novel N,N'-disubstituted thioureas

DOI: 10.1016/0223-5234(94)90209-7

Source and publish data:

European Journal of Medicinal Chemistry p. 127 - 131 (1994)

Update date:2022-07-30

Topics: Synthesis

Authors:

Todoulou

Papadaki-Valiraki

Filippatos

Ikeda Ikeda

De Clercq

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Article abstract of DOI:10.1016/0223-5234(94)90209-7

A series of new N,N'-disubstituted thioureas were prepared and evaluated in vitro for their activity against myxoviruses. Compound N-[4-(3-propoxy-1H-1,2,4-triazol-1-yl)phenyl]-N'-(2-pyrazinyl)thiourea 5d exhibited specific activity against respiratory sy

Full text of DOI:10.1016/0223-5234(94)90209-7

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