Journal of Organic Chemistry p. 6703 - 6709 (1994)
Update date:2022-09-26
Topics: Synthesis Yield Procedure Reaction Conditions Benzophenones Sterically congested
Hollinshead
Nichols
Wilson
Two efficient syntheses of the sterically congested tetraortho-substituted benzophenone portion of balanol 1 (a potent PKC inhibitor) in a protected form are described. Ortho lithiation reactions are employed for the preparation of the required 1,2,3-tris
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