One-step synthesis of 1,2,3,4-tetrahydrobenzo[g]quinazoline-5,10-dione derivatives from vitamin K3

DOI: 10.1248/cpb.42.1730

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1730 - 1735 (1994)

Update date:2022-08-03

Topics: Purification and characterization Optimization and Scale-Up

Authors:

Ohta Ohta

Hinata Hinata

Yamashita

Kawasaki

Jinda Jinda

Horie Horie

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.1730

The reactions of 2-halogenonaphthoquinones (5, 13, 14 and 15) and 2-methyl-1,4-naphthoquinone (20; vitamin K₃) with primary and secondary amines were examined. 1,3-Dialkyl-1,2,3,4-tetrahydrobenzo[g]quinazoline-5,10-diones (9) were obtained in moderate yields by treating 20 with formaldehyde in primary amines. A plausible reaction path-way is also presented.

Full text of DOI:10.1248/cpb.42.1730

NII-Electronic Library Service

Products guided by the article

Product name:2-Hydroxymethyl-3-propylamino-[1,4]naphthoquinone

Cas No:159495-43-9

R&D Labs maybe for 159495-43-9

Changzhou Welton Chemical Co., Ltd,

Contact:0086-519-85910828,85920537,85912897

Address:No.8 Jinlong Road, Binjiang Park, Changzhou, Jiangsu, China.
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd

Contact:+86-533-5415882

Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
ShenZhen InnoSyn Biotech Co.,Ltd

website:http://www.innosyns.com

Contact:+86-755-28351685

Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District
ShenZhen InnoSyn Biotech Co.,Ltd

website:http://www.innosyns.com

Contact:+86-755-28351685

Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District
Jiangsu Cale New Material Co.ltd

Contact:+86-515-88334667/88203550

Address:Zhongshan 3rd Road, Coastal Chemical Industry Park, Yancheng, Jiangsu, China

Relevant to this article

4-Aminocyclopentane-1,3-diols as platforms for diversity: Synthesis of a screening library

Doi:10.1039/c3md00252g
(2014)
Syntheses, structures, and characterization of three new complexes constructed from triazolyl n-heterocyclic ligand

Doi:10.1080/15533174.2013.783857
(2014)
Fe(II)/Fe(III)-Catalyzed Intramolecular Didehydro-Diels-Alder Reaction of Styrene-ynes

Doi:10.1021/acs.joc.7b02672
(2018)
Spectral, ligating properties, and electrical conductivity of some azo-nitroso metal complexes

Doi:10.1080/15533174.2013.776589
()
Optimizing electron transfer mediators based on arylimidazoles by ring fusion: Synthesis, electrochemistry, and computational analysis of 2-aryl-1-methylphenanthro[9,10-d ]imidazoles

Doi:10.1021/ja410865z
(2014)
Controllable Rh(III)-Catalyzed Annulation between Salicylaldehydes and Diazo Compounds: Divergent Synthesis of Chromones and Benzofurans

Doi:10.1021/acs.orglett.6b03355
(2016)

Article Doi