Enantiomerically pure amino alcohols and diamino alcohols from L-aspartic acid. Application to the synthesis of epi- and diepislaframine

Article abstract of DOI:10.1021/jo00101a042

Starting from natural aspartic acid (6) a practical method for the synthesis of enantiomerically pure 3-amino alcohols 8 including 3,4-diamino derivatives is described. After perbenzylation of 6 and reduction of both carboxylates, position 4 of the result