Synthetic Studies on Quinocarcin and Its Related Compounds. 4. Total Synthesis of Enantiomeric Pairs of Quinocarcin and 10-Decarboxyquinocarcin

DOI: 10.1016/S0040-4020(01)80644-X

Source and publish data:

Tetrahedron p. 6239 - 6258 (1994)

Update date:2022-08-03

Topics:

Authors:

Katoh, Tadashi

Kirihara, Masayuki

Nagata, Yuriko

Kobayashi, Yuko

Arai, Katsuko

et al. et al.

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Article abstract of DOI:10.1016/S0040-4020(01)80644-X

The title synthesis was accomplished by featuring (i) aldol coupling of the 3-methylanisole 11 with 5-substituted- or 3,5-disubstituted- 2-formylpyrrolidine 4 or 5, (ii) highly diastereoselective reduction of 1,3-disubstituted isoquinolines 14 and 33 to c

Full text of DOI:10.1016/S0040-4020(01)80644-X

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