Bioorganic and Medicinal Chemistry Letters p. 483 - 486 (1998)
Update date:2022-08-04
Topics:
Liverton, Nigel J.
Armstrong, Donna J.
Claremon, David A.
Remy, David C.
Baldwin, John J.
Lynch, Robert J.
Zhang, Guixiang
Gould, Robert J.
The synthesis and biological activity of a series of 3,6-substituted quinazolinediones and quinazolinones are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of these structures as central templates for nonpeptide RGD mimics.
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