Journal of Medicinal Chemistry p. 4508 - 4517 (1995)
Update date:2022-08-05
Topics:
Senokuchi, Kazuhiko
Nakai, Hisao
Nakayama, Yoshisuke
Odagaki, Yoshihiko
Sakaki, Katsuhito
et al.
Synthesis and structural requirements for good oral activity of a series of para-substituted benzoyl esters of 4-hydroxybenzamidine serine protease inhibitors are described.The structure required for good oral activity was found to be general formula II w
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