A practical synthesis of (R)- and (S)-(E)-4-hydroxyalk-2-enals, cytotoxic products of the microsomal lipid peroxidation

Article abstract of DOI:10.1016/S0957-4166(00)86245-X

The chemical synthesis of some (S)- and (R)-(E)-4-hydroxyalk-2-enals, important products of lipid peroxidation (LPO), has been carried out via enantiomerically pure 2-benzoyloxyaldehydes, chiral key intermediates obtained from two diastereomeric diepoxide