Inhibitors of Glycinamide Ribonucleotide Formyltransferase as Potential Cytotoxic Agents. Synthesis of 5-Deaza-5,6,7,8-tetrahydrohomofolic Acid, 5-Deaza-5,6,7,8-tetrahydroisohomofolic Acid, and 10-Formyl-5-deaza-5,6,7,8-tetrahydroisohomofolic Acid

DOI: 10.1021/jo00102a039

Source and publish data:

Journal of Organic Chemistry p. 7092 - 7095 (1994)

Update date:2022-09-26

Topics:

Authors:

Taylor, Edward C.

Yoon, Cheol-min

Hamby, James M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00102a039

Syntheses of three new analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF, Lometrexol)-5-deaza-5,6,7,8-tetrahydrohomofolic acid (11), 5-deaza-5,6,7,8-tetrahydroisohomofolic acid (16a), and 10-formyl-5-deaza-5,6,7,8-tetrahydroisohomofolic acid (1

Full text of DOI:10.1021/jo00102a039

Products guided by the article

Product name:Diethyl N-<4-pyrimidin-6-yl)ethen-1-yl>-N-formylamino>benzoyl>glutamate

Cas No:159720-87-3

R&D Labs maybe for 159720-87-3

Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Shanghai Micro-mega Industry Co., Ltd.

Contact:0086-21-34628682;57153848

Address:Rm413,No.413,West Meilong Road, Minhang District,Shanghai P R China
Nanyang Tianhua pharmaceutical Co.,Ltd.

Contact:+8618639816203

Address:Longsheng Industrial Park
Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai
Leshan Kai Yada Photoelectric Technology Co., Ltd.,

website:http://www.kydmaterials.com

Contact:0833-5603116

Address:Airport road Jiajiang county, Sichuan province,China

Relevant to this article

Seven-co-ordinate Dibromo Complexes of Molybdenum(II) and Tungsten(II) derived from . Crystal Structures of the isostructural Complexes *CH2Cl2 (X = Br or I)

Doi:10.1039/DT9940003493
(1994)
Total Synthesis of ACRL Toxin IIIb: A Protocol for Parlaying Aldols into Synthons Containing Three Stereocenters Having an Relationship

Doi:10.1021/jo00104a001
(1994)
Strategies for the synthesis of C-disaccharides containing D and L sugars

Doi:10.1016/0040-4039(94)80107-X
(1994)
Branch-selective alkene hydroarylation by cooperative destabilization: Iridium-catalyzed ortho-alkylation of acetanilides

Doi:10.1002/anie.201506581
(2015)
A facile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using the hydrolytic kinetic resolution method

Doi:10.1016/j.tetasy.2010.11.011
(2010)
Enantio- and Regioselective NiH-Catalyzed Reductive Hydroarylation of Vinylarenes with Aryl Iodides

Doi:10.1002/anie.202010386
(2020)

Article Doi