Stereoselective synthesis and inhibitor properties towards human leucocyte elastase of chiral β-peptidyl trifluoromethyl alcohols

DOI: 10.1016/0957-4166(94)80061-8

Source and publish data:

Tetrahedron Asymmetry p. 1099 - 1110 (1994)

Update date:2022-08-03

Topics: Chiral Stereoselective synthesis Experimental terms

Authors:

Begue Begue

Bonnet-Delpon

Fischer-Durand

Amour Amour

Reboud-Ravaux

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(94)80061-8

The synthesis of chiral peptidyl trifluoromethyl alcohols 9 and 10 was performed from easily available epoxy ethers 3, through different stereocontrol of the reduction of the azido ketone 4. One stereoisomer in each pair of the diastereoisomeric peptidyl

Full text of DOI:10.1016/0957-4166(94)80061-8

Products guided by the article

Product name:benzyl [(2S)-3-methyl-1-oxo-1-{[(2R,3S)-1,1,1-trifluoro-2-hydroxy-5-phenylpentan-3-yl]amino}butan-2-yl]carbamate

Cas No:159949-02-7

R&D Labs maybe for 159949-02-7

Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
Nanjing Qirui Material Co., Ltd.

Contact:+86-25-52320053

Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
HENAN NEW BLUE CHEMICAL CO.,LTD

website:http://www.newbluechem.com

Contact:86-371-55170693/55170694

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

Relevant to this article

2,4-Dialkyl-8,9,10,11-tetrahydrobenzo[g]pyrimido[4,5-c]isoquinoline-1,3,7, 12(2H,4H)-tetraones as new leads against Mycobacterium tuberculosis

Doi:10.1016/j.ejmech.2014.03.024
(2014)
Selective synthesis of 6-ribo- (and xylo) pyrano and furano aminopyrimidines. Anticancer and anti-aids activities

Doi:10.1080/15257779408013254
(1994)
Palladium-catalyzed carbonylative synthesis of quinazolines: Silane act as better nucleophile than amidine

Doi:10.1016/j.mcat.2021.111627
(2021)
Metal-free diimide reduction of alkenylphosphonates: simple and efficient protocol for the synthesis of α-substituted ethylphosphonates

Doi:10.1016/j.tetlet.2016.02.057
(2016)
Total Synthesis of AB3217-A, a Novel Anti-mite Substance, via Intramolecular Glycosylation

Doi:10.1016/S0040-4039(00)76839-0
(1994)
Pd-carbene migratory insertion: Application to the synthesis of trifluoromethylated alkenes and dienes

Doi:10.1002/chem.201304143
(2014)

Article Doi