Journal of the Chemical Society. Perkin transactions I p. 2525 - 2532 (1994)
Update date:2022-07-30
Topics:
Hartzoulakis, Basil
Gani, David
Arndt-Eistert homologation of suitably protected (2S,3S)-3-methylaspartic acid occurs with retention of configuration at C-3 to give, ultimately, (2S,3R)-3-methylglutamic acid. (2S,3R)-3-Methylglutamic acid was also prepared in good yield via the conjugate addition of the lithiated anion of the bis-lactim ether of cyclo-(R-Val-Gly) to methyl (E)-butenoate.The analogous reaction performed using isopentyl (Z)-butenoate ultimately gave (2S,3S)-3-methylglutamic acid.Both conjugate additions occured with high diastereoselectivity.
View MoreContact:+86-021-50792271
Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202
website:https://www.synose.com/
Contact:86-579-82275537
Address:No.1958 Liyu Road , jinhua,zhejiang,China
Shanghai Puda Chemical Co.,Ltd
Contact:+86+571+56565965
Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
Yixing Bluwat Chemicals Co., Ltd.
Contact:+86 510 87821568
Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Tai zhou world Pharm & Chem Co., Ltd
Contact:+86-576-85301198
Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Doi:10.1016/S0040-4020(01)89277-2
(1994)Doi:10.1002/adsc.201600351
(2016)Doi:10.1016/j.dyepig.2014.02.019
(2014)Doi:10.1016/j.bmcl.2015.04.103
(2015)Doi:10.1080/00397919408010611
(1994)Doi:10.1016/j.procbio.2015.11.020
(2016)
