Titanium (IV) catalysis in the reduction of phosphine oxides

Article abstract of DOI:10.1016/S0040-4039(00)75855-2

Phosphine oxides can be reduced by triethoxysilane, or more conveniently polymethylhydrosiloxane, and catalytic titanium (IV) isopropoxide and provides a system for the efficient one-pot generation of phosphonium salts; the reduction occurs with retention of configuration at phosphorus.