Synthesis and mechanistic evaluation of 7-vinylidenecephem sulfones as β-lactamase inhibitors

DOI: 10.1021/ja00103a010

Source and publish data:

Journal of the American Chemical Society p. 10955 - 10965 (1994)

Update date:2022-08-04

Topics:

Authors:

Buynak, John D.

Khasnis, Dipti

Bachmann, Brian

Wu, Kuangcong

Lamb, Grady

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00103a010

Representative 7-vinylidenecephalosporins 1 were synthesized from 7-aminocephalosporanic acid and were biologically evaluated as β-lactamase inhibitors. These chiral allenes were prepared stereospecifically from a cephalosporin-derived propargylic triflat

Full text of DOI:10.1021/ja00103a010

Products guided by the article

Product name:benzhydryl 7α-(2'-deuterioethynyl)-7β-hydroxycephalosporanate

Cas No:160032-80-4

R&D Labs maybe for 160032-80-4

Taizhou Sunny Chemical Co.,Ltd

Contact:+86-523-86920899 +86-13951172783

Address:No.11 Xingyuang road, Gaoyong Chemical Industry Park, Gaogang Jiangsu China
Xi'an Tizan Tech & Industry Co., Ltd.

Contact:86-18629066522

Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.
Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Jiangsu Wanlong Chemical Co., Ltd.

website:http://www.wanlongchem.com

Contact:+86-511-86810993 0086-511-8681 0888;

Address:Quanzhou Town, Danyang City, Jiangsu

Relevant to this article

Sustainable Manganese-Catalyzed C?H Activation/Hydroarylation of Imines

Doi:10.1002/cctc.201800144
(2018)
Copper-catalyzed intermolecular trifluoromethylazidation of alkenes: Convenient access to CF₃-containing alkyl azides

Doi:10.1002/anie.201309991
(2014)
Epoxidation of propylene with nitrous oxide on Rb₂SO₄-modified iron oxide on silica catalysts

Doi:10.1016/j.jcat.2007.01.001
(2007)
Sulphated silica tungstic acid as a highly efficient and recyclable solid acid catalyst for the synthesis of tetrahydropyrimidines and dihydropyrimidines

Doi:10.1016/j.molcata.2014.02.019
(2014)
Synthesis and structure-activity relationship of naphtho[1,2- B]furan-2-carboxamide derivatives as melanin concentrating hormone receptor 1 antagonists

Doi:10.1248/cpb.c13-00486
(2013)
Four-legged piano stool molybdenum(II) compounds without carbonyl ligands. 4. Cyclopentadienylmolybdenum(II) complexes with 16-electron and 18-electron configurations

Doi:10.1021/om960331d
(1996)

Article Doi