1-Acyloxy-2(1H)-pyrimidine-2-thiones as novel radical precursors

DOI: 10.1016/0040-4039(94)88211-8

Source and publish data:

Tetrahedron Letters p. 7009 - 7012 (1994)

Update date:2022-08-02

Topics:

Authors:

Liebscher, Juergen

Riemer, Beate

Bendig, Juergen

Stoesser, Reinhard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(94)88211-8

Reaction of 3-isothiocyanato-2-propeniminium perchlorates 1 with hydroxylamine gives 1-hydroxy-2(1H)-pyrimidine-2-thiones 2 which can be O-acylated. The resulting 1-acyloxy-2(1H)-pyrimidine-2-thiones 4 are novel precursors for organic radicals. Their photochemical homolysis is studied and affords disulfides 5, 2-alkylthiopyrimidines 6 and alkanes 7 and 8.

Full text of DOI:10.1016/0040-4039(94)88211-8

Products guided by the article

Product name:1-Hydroxy-4-phenyl-1H-pyrimidine-2-thione

Cas No:160110-77-0

R&D Labs maybe for 160110-77-0

Shenzhen Sunrising Industry Co., ltd.

Contact:+86 755 86571158 / 86571159 / 86571160

Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
Cangzhou Senary Chemical Science-tech Co., Ltd

Contact:+86-317-3563899, 3563699

Address:168 Jinde Road, Cangzhou, Hebei, China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
WENZHOU M&C FOREIGN TRADE CO.,LTD.

Contact:+86-577-88862917

Address:No.8 Liming West Road,Wenzhou,zhejiang,China

Relevant to this article

A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmor

Doi:10.1021/acs.jmedchem.8b00900
(2018)
Chemical synthesis and functional characterization of a new class of ceramide analogues as anti-cancer agents

Doi:10.1016/j.bmc.2019.02.030
(2019)
Synthesis of 6-benzylidene-2-(α,α-diphenyl-α-hydroxyacetyl)-thiazolo[3,2-b]-s-tr iazol-5-ones as potential biologically active compounds

Doi:10.1002/ardp.19943271214
(1994)
SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH

Doi:10.1135/cccc19951196
(1995)
Synthesis of the tetrasaccharide repeating unit of the O-glycan from the polar flagellum flagellin of Azospirillum brasilense Sp7

Doi:10.1016/j.carres.2014.06.019
(2014)
Substrate-directed hydroacylation: Rhodium-catalyzed coupling of vinylphenols and nonchelating aldehydes

Doi:10.1002/anie.201309987
(2014)

Article Doi