Fungal metabolites. XVII. Synthesis and NMR study of ion channel-forming peptides, trichosporin B-VIa and its derivative

DOI: 10.1248/cpb.42.1258

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1258 - 1263 (1994)

Update date:2022-08-03

Topics: Derivative NMR Study Ion channel

Authors:

Nagaoka Nagaoka

Iida Iida

Fujita Fujita

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Article abstract of DOI:10.1248/cpb.42.1258

A membrane-modifying peptide antibiotic, trichosporin B-VIa, having catecholamine secretion-inducing activity on bovine adrenal chromaffin cells has been synthesized. Aib¹⁴-Trichosporin B-Vla, in which Pro¹⁴ was replaced by Aib, has

Full text of DOI:10.1248/cpb.42.1258

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