Biocatalytic resolutions of β-fluoroalkyl-β-amino acids

DOI: 10.1016/0957-4166(94)80063-4

Source and publish data:

Tetrahedron Asymmetry p. 1119 - 1126 (1994)

Update date:2022-08-03

Topics:

Authors:

Soloshonok

Kirilenko

Fokina Fokina

Shishkina

Galushko

Kukhar Kukhar

Svedas Svedas

Kozlova Kozlova

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Article abstract of DOI:10.1016/0957-4166(94)80063-4

N-Phenylacetyl derivatives of β-fluoroalkyl-β-alanines 6 were synthesized and biocatalytically resolved to the corresponding enantiopure β-amino acids 7,9 with the aid of penicillin acylase (EC 3.5.1.11) from Escherichia coli. In substrates 6 the enantios

Full text of DOI:10.1016/0957-4166(94)80063-4

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