Monocarboxylates of 3-methylidene-β-lactams: Synthesis and unusual oxidative rearrangement into a spiro[azetidine-3,3'-pyrrolidine]derivative

Article abstract of DOI:10.1002/hlca.19940770808

Reaction of the 3-silylated β-lactams 1 with glycoxalates gives bis-lactam 3, but the same reaction in the presence of 1 equiv. of Me₃SiCl leads to the formation of the disilylated adducts 5. The latter is desilylated by (Bu₄N)F yiel