Tetrahedron p. 10289 - 10298 (1994)
Update date:2022-08-05
Topics:
Commercon, Alain
Bourzat, Jean-Dominique
Bezard, Daniel
Vuilhorgne, Marc
The structures and synthesis of the four major human metabolites of docetaxel are reported. These metabolites, i.e. compounds 3, 4a,b and 5, are side-chain oxidation derivatives. They were prepared by partial synthesis from the previously described amino-taxoid 8 using mixed-carbonates as acylation reagents. In vitro biological activities are detailed.
View MoreContact:+86-10-83993285
Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Jiaxing Trustworthy Import And Export Co.,Ltd
Contact:+86-573-82030555
Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
SHAANXI TOP PHARM CHEMICAL CO.LTD
Contact:+86-029-85733403
Address:No.108 ,west sector,south er huan,xi'an,china
Nanjing Yuance Industry&Trade Co., Ltd.
website:http://www.njyuance.cn/
Contact:+86-25-85439097
Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
LinHai Cina Chemical Co., LTD.
Contact:0576-85580989
Address:Pharma-chem zone,Duqiao,Linhai,Zhejiang,China
Doi:10.1021/ja00713a038
(1970)Doi:10.1016/j.dyepig.2014.02.001
(2014)Doi:10.1016/j.bmcl.2014.01.050
(2014)Doi:10.1002/anie.202106716
(2021)Doi:10.1021/jo500536b
(2014)Doi:10.1016/j.bmcl.2014.03.043
(2014)
