Reaction of (1S,2S)-2-amino-1-phenyl-1,3-propanediol with thioacids under the Mitsunobu reaction condition

Article abstract of DOI:10.1016/S0040-4020(97)00672-8

The Mitsunobu thioesterification was applied to the title 2-amino-1,3-propanediol (1). The regio- and stereochemistry of the reaction was investigated in correlation with the nature of substituents attached to the nitrogen.