Journal of Medicinal Chemistry p. 3492 - 3502 (1994)
Update date:2022-08-05
Topics:
Tsutsumi, Seiji
Okonogi, Tsuneo
Shibahara, Seiji
Ohuchi, Shokichi
Hatsushiba, Emiko
et al.
The preparation and in vitro prolyl endopeptidase (PEP) inhibitory activity of a series of α-keto heterocyclic compounds is described.The design is based on the introduction of α-keto heterocycles at the C-terminal end of substrate-like peptides.Many of t
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