Evaluation of some anti-inflammatory pyrimidobenzimidazoles synthesized via novel Tin(II) chloride-hydrochloric acid assisted water addition and reduction of 4,4,6-trimethyl-1-(2-nitroaryl)-1,4-dihydropyrimidine-2(3H)-thiones

Article abstract of DOI:10.1055/s-1994-25667

4,4,6-Trimethyl-1-(2-nitroaryl)-1,4-dihydropyrimidine-2(3H)-thiones (Ia-c) on reduction with Al/Hg amalgam gave 1-(2-aminoar)yl)-4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)-thiones (IIa-c). The reduction of 4,4,6-trimethyl-1-(2-nitroaryl or 4-nitrophenyl