A New Method for Hydroxymethylene Peptide Isostere Synthesis: Asymmetric Synthesis of Statine

DOI: 10.1016/S0040-4039(00)78545-5

Source and publish data:

Tetrahedron Letters p. 9371 - 9374 (1994)

Update date:2022-08-03

Topics:

Authors:

Williams, Robert M.

Colson, Pierre-Jean

Zhai, Weixu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)78545-5

The asymmetric synthesis of (-)-Statine is described.The key step of the synthesis involves the coupling of hemi-acetal 6 with the ketene silyl acetal of methyl acetate.

Full text of DOI:10.1016/S0040-4039(00)78545-5

Products guided by the article

Product name:(3S,5S,6R)-3-Cyclohexylmethyl-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester

Cas No:161123-45-1

R&D Labs maybe for 161123-45-1

Chiral Quest (Suzhou) Company Ltd

website:http://www.chiralquest.com

Contact:+86-0512-62956066

Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Rely Chemicals Ltd.

Contact:+86-518-81061113

Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
Valiant Fine Chemicals Co., Ltd.

Contact:+86 535 6101878/6374484

Address:11 Wuzhishan Rd.,YTETDZ,Yantai,264006,Shandong,China
WUXI HONOR SHINE CHEMICAL CO.,LTD

Contact:+86-510-83593312

Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
Acros Pharmatech Limited

website:http://www.acrospharmatech.com

Contact:+1-3234804688

Address:Flat/RM 1502,Easey Commercial building 253-261 Hennessy Road,Wanchai，HongKong

Relevant to this article

A fluorescent probe for thiols based on aggregation-induced emission and its application in live-cell imaging

Doi:10.1016/j.dyepig.2014.04.020
(2014)
Phosphine-catalyzed asymmetric formal [4+2] tandem cyclization of activated dienes with isatylidenemalononitriles: Enantioselective synthesis of multistereogenic spirocyclic oxindoles

Doi:10.1002/adsc.201301070
(2014)
Total Synthesis of Microginin, an Angiotensin-Converting Enzyme Inhibitory Pentapeptide from the Blue-Green Alga Microcystis aeruginosa

Doi:10.1016/S0040-4020(01)89431-X
(1994)
A new approach for the synthesis of N-sulfonyl hydantoins

Doi:10.1016/j.tetlet.2014.04.110
(2014)
α,α-Alkylation-Halogenation and Dihalogenation of Sulfoxonium Ylides. A Direct Preparation of Geminal Difunctionalized Ketones

Doi:10.1002/chem.201704609
(2017)
Facile access to libraries of diversely substituted 2-aryl-benzoxazoles/benzothiazoles from readily accessible aldimines via cyclization/cross coupling in imidazolium-ILs with Pd(OAc)2 or NiCl2 (dppp) as catalyst

Doi:10.1016/j.tetlet.2019.151509
(2020)

Article Doi