A New Method for Hydroxymethylene Peptide Isostere Synthesis: Asymmetric Synthesis of Statine

DOI: 10.1016/S0040-4039(00)78545-5

Source and publish data:

Tetrahedron Letters p. 9371 - 9374 (1994)

Update date:2022-08-03

Topics:

Authors:

Williams, Robert M.

Colson, Pierre-Jean

Zhai, Weixu

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Article abstract of DOI:10.1016/S0040-4039(00)78545-5

The asymmetric synthesis of (-)-Statine is described.The key step of the synthesis involves the coupling of hemi-acetal 6 with the ketene silyl acetal of methyl acetate.

Full text of DOI:10.1016/S0040-4039(00)78545-5

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