Asymmetric Synthesis of α-Trifluoromethyl Substituted Aminoacids via 3-Hydroxy-3-trifluoromethyl-2,5-diketopiperazines

DOI: 10.1016/0957-4166(94)80055-3

Source and publish data:

Tetrahedron Asymmetry p. 1051 - 1060 (1994)

Update date:2022-08-02

Topics:

Authors:

Sewald, Norbert

Seymour, Liza C.

Burger, Klaus

Osipov, Sergey N.

Kolomiets, Alexey F.

Fokin, Alexander V.

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Article abstract of DOI:10.1016/0957-4166(94)80055-3

Key words: Methyl trifluoropyruvate; asymmetric synthesis; homochiral α-trifluoromethyl substituted diketopiperazines; homochiral α-trifluoromethyl substituted aminoacids The diastereoselective reaction of organometallic compounds (RMgX, R2Cd) with in sit

Full text of DOI:10.1016/0957-4166(94)80055-3

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