European Journal of Medicinal Chemistry p. 47 - 55 (2014)
Update date:2022-08-03
Topics:
S?awiński, Jaros?aw
Pogorzelska, Aneta
Zo?nowska, Beata
Brozewicz, Kamil
Vullo, Daniela
Supuran, Claudiu T.
A series of novel 5-substituted 2,4-dichlorobenzenesulfonamides 5a-c, 6a-d, 7a-j and 10a-i have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and tumo
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