Synthesis and Biological Evaluation of Both Enantiomers of Dynemicin A Model Compound

DOI: 10.1016/0040-4020(95)00521-9

Source and publish data:

Tetrahedron p. 9339 - 9352 (1995)

Update date:2022-08-02

Topics: Synthesis Enantiomers Biological Evaluation Dynemicin A Model Compound

Authors:

Nishikawa, Toshio

Yoshikai, Maki

Obi, Kazuyo

Kawai, Takatoshi

Unno, Ryoichi

et al. et al.

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Article abstract of DOI:10.1016/0040-4020(95)00521-9

A novel 1,4-asymmetric induction was developed for the synthesis of chiral dynemicin A model compound.By using this reaction, both enantiomers were synthesized from chiral alcohol prepared by lipase catalyzed resolution.The biological activities of these compounds were examined.

Full text of DOI:10.1016/0040-4020(95)00521-9

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