Asymmetric Syntheses of β-Lactams and Determination of Their Absolute Configuration

DOI: 10.1016/0040-4039(94)02294-L

Source and publish data:

Tetrahedron Letters p. 497 - 500 (1995)

Update date:2022-08-03

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Authors:

Niu, Chuansheng

Miller, Marvin J.

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Article abstract of DOI:10.1016/0040-4039(94)02294-L

Reactions of chiral imines derived from D-glyceraldehyde and threonine derivatives with Oxglycylchloride gave optically active cis-substituted β-lactams.The absolute configuration of key intermediates were determined by X-ray analysis and chemical degradation. - Key words: Asymmetric syntheses, D-glyceraldehyde, threonine, β-lactam, Staudinger reaction

Full text of DOI:10.1016/0040-4039(94)02294-L

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