Chemical and Pharmaceutical Bulletin p. 1305 - 1309 (1991)
Update date:2022-07-30
Topics:
Ikeda
Kawai
Achiwa
The syntheses of novel penta-O-acetyl-N-glycoloylneuraminyl- and penta-O-acetyl-3-deoxy-n-glycero-D-galacto-2-nonulopyranosonic acid-(α 2 → 6)-D-glucosamine-4-phosphate analogues of lipid A containing sialic acid in place of 3-deoxy-D-manno-2-octulosonic acid are described. Preliminary examination of the biological activity revealed that two synthetic disaccharides showed mitogenic activities and weak antitumor activities.
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