
Chemical and Pharmaceutical Bulletin p. 1545 - 1547 (1994)
Update date:2022-08-03
Topics: Chiral center Total synthesis Experimental Practical
Nagai
Yoshimura
Hibi
Kikuchi
Abe
Asada
Yamauchi
Hida
Higashi
Hishinuma
Yamanaka
Practical and facile total syntheses of the remarkably unstable (R)-(+)- 14-hydroxy-4, 14-retro-retinol [(R)-14HRR] 1 and of its enantiomer 2 have been achieved via an acid-catalyzed dehydration reaction of the respective tetraeneol intermediates 10 and i
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