Journal of Medicinal Chemistry p. 1229 - 1241 (1995)
Update date:2022-08-03
Topics:
Palmer
Van Zijl
Denny
Wilson
5-[N,N-Bis(2-chloroethyl)amino]-2,4-dinitrobenzamide (1; SN 23862) is a novel bioreductive drug whose selective toxicity for hypoxic cells appears due to oxygen-inhibited enzymatic reduction of one of the nitro groups to the corresponding amine or hydroxy
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Doi:10.1139/v82-093
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