
Tetrahedron Letters p. 6097 - 6100 (1994)
Update date:2022-08-05
Topics:
Begue, Jean-Pierre
Bonnet-Delpon, Daniele
Rock, Michael H.
The chlorine atom in chlorodifluoromethyl epoxy ethers is unusually reactive towards butyllithium. This reactivity has been used to develop a concise synthesis of gem-difluoro-2-ethoxy allylic alcohols from the commercially available ethylchlorodifluoroacetate.
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