First Demonstration of a Carbocation-Olefin Cyclization Route to the Lanosterol Series

DOI: 10.1016/0040-4039(94)88450-1

Source and publish data:

Tetrahedron Letters p. 9149 - 9152 (1994)

Update date:2022-07-30

Topics:

Authors:

Corey, E. J.

Lee, Jaemoon

Lin, David R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(94)88450-1

A silicon-assisted double carbocation-olefin cyclization reaction was used as the key step (10->11) in a simple, convergent and enatioselective total synthesis of lanostenol (1).

Full text of DOI:10.1016/0040-4039(94)88450-1

Products guided by the article

Product name:[(E)-(S)-1-[(1R,3aR,7aR)-1-((R)-1,5-Dimethyl-hexyl)-3a,7a-dimethyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]-6-((S)-3,3-dimethyl-oxiranyl)-4-methyl-hex-3-enyl]-dimethyl-phenyl-silane

Cas No:162460-33-5

R&D Labs maybe for 162460-33-5

QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071
Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
He Bei Shun Er Chemical Co., LTD.

Contact:86-0311-86996932/86860168

Address:No 18,North street
Wuhan HengHeDa Pharm Co., Ltd

Contact:86-27-84888681

Address:Wuhan economic & technology development zone
UK SHAREPOINT INTERNATIONAL TRADE CO., LTD(expird)

Contact:44-20-31299469

Address:FLAT 107 25 INDESCON SQUARE LONDON UNITED KINGDOM E14 9DG

Relevant to this article

Synthesis of new thiobarbituric acid derived spiroheterobicyclic compounds and their antimicrobial activity

Doi:10.1002/ddr.21172
(2014)
PREPARATION AND PROPERTIES OF DERIVATIVES OF DITHIOLYLIDENE-(4'-PHENYLDIAZONIUM)ACETONITRILE

Doi:10.1007/BF01165004
(1994)
Stereocontrol in organic synthesis using silicon-containing compounds. A formal synthesis of prostaglandins controlling the stereochemistry at C-15 using a silyl-to-hydroxy conversion following a stereochemically convergent synthesis of an allylsilane

Doi:10.1039/a804276d
(1998)
Rh₂(OAc)₄ and chiral phosphoric acid cocatalyzed highly diastereo- and enantioselective four-component reactions: Facile synthesis of chiral α,β-diamino acid derivatives

Doi:10.1055/s-0033-1341051
(2014)
New Mechanistic Evidence on the Reaction between Sulfonylallenes and Nitrile Oxides

Doi:10.1021/jo00105a055
(1994)
Synthesis and absolute configuration of the enantiomers of 7-fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone (flosequinan)

Doi:10.1248/cpb.42.2157
(1994)

Article Doi