First Demonstration of a Carbocation-Olefin Cyclization Route to the Lanosterol Series

DOI: 10.1016/0040-4039(94)88450-1

Source and publish data:

Tetrahedron Letters p. 9149 - 9152 (1994)

Update date:2022-07-30

Topics:

Authors:

Corey, E. J.

Lee, Jaemoon

Lin, David R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(94)88450-1

A silicon-assisted double carbocation-olefin cyclization reaction was used as the key step (10->11) in a simple, convergent and enatioselective total synthesis of lanostenol (1).

Full text of DOI:10.1016/0040-4039(94)88450-1

Products guided by the article

Product name:[(E)-(S)-1-[(1R,3aR,7aR)-1-((R)-1,5-Dimethyl-hexyl)-3a,7a-dimethyl-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl]-6-((S)-3,3-dimethyl-oxiranyl)-4-methyl-hex-3-enyl]-dimethyl-phenyl-silane

Cas No:162460-33-5

R&D Labs maybe for 162460-33-5

Shandong LuZhou Amino Acid Co., Ltd

Contact:86-539-2218025

Address:yishui economic and technical development zone zhenxing south road
Wuhan Soleado Technology Co.,Ltd.

Contact:86-2783341481 18971291927

Address:RM2405 Unit 1 Builing 1, Taiyin Tower, Changqing Road,Wuhan China
Chengdu Boon Stream Chemical Industry Co.,Ltd.

Contact:+86-28-83156758

Address:No.859,Dongzikou Road,Jinniu District,Chengdu,Sichuan,P.R.China
Beijing Mesochem Technology Co.,LTD

website:http://www.mesochem.com

Contact:0086-10-57862036

Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Suzhou Ryan Pharmachem Technology Co.,Ltd

Contact:+86-0512-68780025

Address:B-301,No.2 Taishan Road,Suzhou New District,Jiangsu,P.R. China

Relevant to this article

Synthesis of new thiobarbituric acid derived spiroheterobicyclic compounds and their antimicrobial activity

Doi:10.1002/ddr.21172
(2014)
PREPARATION AND PROPERTIES OF DERIVATIVES OF DITHIOLYLIDENE-(4'-PHENYLDIAZONIUM)ACETONITRILE

Doi:10.1007/BF01165004
(1994)
Stereocontrol in organic synthesis using silicon-containing compounds. A formal synthesis of prostaglandins controlling the stereochemistry at C-15 using a silyl-to-hydroxy conversion following a stereochemically convergent synthesis of an allylsilane

Doi:10.1039/a804276d
(1998)
Rh₂(OAc)₄ and chiral phosphoric acid cocatalyzed highly diastereo- and enantioselective four-component reactions: Facile synthesis of chiral α,β-diamino acid derivatives

Doi:10.1055/s-0033-1341051
(2014)
New Mechanistic Evidence on the Reaction between Sulfonylallenes and Nitrile Oxides

Doi:10.1021/jo00105a055
(1994)
Synthesis and absolute configuration of the enantiomers of 7-fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone (flosequinan)

Doi:10.1248/cpb.42.2157
(1994)

Article Doi