Application of the Mitsunobu-Type Condensation Reaction to the Synthesis of Phosphonate Derivatives of Cyclohexenyl and Cyclohexanyl Nucleosides

Article abstract of DOI:10.1021/jo00111a010

1,4-trans-Cyclohexanediol has been used as starting material for the synthesis of cyclohexenyl and cyclohexanyl nucleosides functionalized with a OCH2P(O)(OH)2 moiety in a 1,4-cis relationship with the heterocyclic base.The methodology used is based on th