Preparation of 7-Modified docetaxel analogs using electrochemistry

DOI: 10.1016/0040-4039(94)88366-1

Source and publish data:

Tetrahedron Letters p. 9709 - 9712 (1994)

Update date:2022-08-02

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Authors:

Pulicani, Jean-Pierre

Bouchard, Herve

Bourzat, Jean-Dominique

Commercon, Alain

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Article abstract of DOI:10.1016/0040-4039(94)88366-1

The electrochemical reduction of 7α -iodo docetaxel at E- 1.3V vs. SCE in methanol in the presence of lithium chloride and hydrochloric acid leads predominantiy to 7-deoxy-ocetaxel 9. When the electroreduction is conducted at E-1.7V vs. SCE in the presenc

Full text of DOI:10.1016/0040-4039(94)88366-1

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