
Tetrahedron p. 1017 - 1032 (1995)
Update date:2022-07-30
Topics: Synthesis Stereoselective Epimeric
Huffman, John W.
Kenneth Banner
Zoorob, Grace K.
Howard Joyner
Reggio, Patricia H.
Martin, Billy R.
Compton, David R.
Both C9 epimers of Δ7-HTC (3 and 4) have been synthesized from Δ8-THC methyl ether (12). Hydroboration of 12 gave a mixture of stereoisomeric 8-hydroxyhexahydrocannabinols. The 8α-ol was converted into the 9β-methyl epimer (4) of Δ
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