First Enantioselective Synthesis of (-)-Akagerine by a Chemoenzymatic Approach

DOI: 10.1021/jo00113a034

Source and publish data:

Journal of Organic Chemistry p. 2506 - 2513 (1995)

Update date:2022-08-04

Topics: Synthesis Chiral Chemoenzymatic approach Enantioselective synthesis Experimental Approach

Authors:

Danieli, Bruno

Lesma, Giordano

Mauro, Marina

Palmisano, Giovanni

Passarella, Daniele

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00113a034

(-)-Akagerine (1) was synthesized in an efficient and stereocontrolled fashion from the readily available (1S,2R)-cyclohexenedimethanol monoacetate 4.Key steps were the cleavage of the C(17)/C(18) bond of a 14a and the regio- and stereoselective cyclizati

Full text of DOI:10.1021/jo00113a034

Products guided by the article

Product name:(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Cas No:162757-77-9

R&D Labs maybe for 162757-77-9

SuZhou Hua-Emy Chemical Import and Export Co., LTD.

Contact:+86-512-88804994; +86-512-88804550;

Address:710, Building B, International Trade Center, 12 Huanghelu, Changshu, Jiangsu,China
JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD

website:http://www.xypharm.com/

Contact:+86-515-84383317

Address:Chenli Road,Costal Chemical Area Binhai,Yancheng, Jiangsu,China
shanghai hekang chemical co.ltd

Contact:021-54173790

Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Chemtrade International ( China )

Contact:+86-532-86893005

Address:Rm 2-501, Huaxia Zonghe Building, No. 410 JInggangshan Road, Huangdao

Relevant to this article

Ureidopeptide-based Bronsted bases: Design, synthesis and application to the catalytic enantioselective synthesis of β-amino nitriles from (arylsulfonyl)acetonitriles

Doi:10.1002/chem.201304877
(2014)
Synthesis of pyridine- and 2-oxazoline-functionalized vinyl polymers by alane-based frustrated lewis pairs

Doi:10.1055/s-0033-1341248
(2014)
Serendipitous discovery of a cascade approach to perhydrodibenzofuranones related to the natural product incarviditone

Doi:10.1055/s-0033-1341081
(2014)
A recyclable polymer-supported ruthenium catalyst for the oxidative degradation of bisphenol A in water using hydrogen peroxide

Doi:10.1039/c0nj00583e
(2011)
Doi:10.1021/jo01255a008
(1969)
Ruthenium-catalyzed selective synthesis of monoalkylated barbituric acids through “borrowing hydrogen” methodology

Doi:10.1016/j.tetlet.2017.01.070
(2017)

Article Doi