First Enantioselective Synthesis of (-)-Akagerine by a Chemoenzymatic Approach

DOI: 10.1021/jo00113a034

Source and publish data:

Journal of Organic Chemistry p. 2506 - 2513 (1995)

Update date:2022-08-04

Topics: Synthesis Chiral Chemoenzymatic approach Enantioselective synthesis Experimental Approach

Authors:

Danieli, Bruno

Lesma, Giordano

Mauro, Marina

Palmisano, Giovanni

Passarella, Daniele

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00113a034

(-)-Akagerine (1) was synthesized in an efficient and stereocontrolled fashion from the readily available (1S,2R)-cyclohexenedimethanol monoacetate 4.Key steps were the cleavage of the C(17)/C(18) bond of a 14a and the regio- and stereoselective cyclizati

Full text of DOI:10.1021/jo00113a034

Products guided by the article

Product name:(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Cas No:162757-77-9

R&D Labs maybe for 162757-77-9

Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Beijing Mediking Biopharm Co., Ltd.

Contact:+86-10-89753524/81760121/81769521

Address:Hongxianghong Incubator, Beiqijia Town, Changping district, Beijing, China
Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.

Contact:+86-21-61353236

Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA

Relevant to this article

Ureidopeptide-based Bronsted bases: Design, synthesis and application to the catalytic enantioselective synthesis of β-amino nitriles from (arylsulfonyl)acetonitriles

Doi:10.1002/chem.201304877
(2014)
Synthesis of pyridine- and 2-oxazoline-functionalized vinyl polymers by alane-based frustrated lewis pairs

Doi:10.1055/s-0033-1341248
(2014)
Serendipitous discovery of a cascade approach to perhydrodibenzofuranones related to the natural product incarviditone

Doi:10.1055/s-0033-1341081
(2014)
A recyclable polymer-supported ruthenium catalyst for the oxidative degradation of bisphenol A in water using hydrogen peroxide

Doi:10.1039/c0nj00583e
(2011)
Doi:10.1021/jo01255a008
(1969)
Ruthenium-catalyzed selective synthesis of monoalkylated barbituric acids through “borrowing hydrogen” methodology

Doi:10.1016/j.tetlet.2017.01.070
(2017)

Article Doi