Journal of Medicinal Chemistry p. 771 - 793 (1995)
Update date:2022-07-30
Topics:
Breslin
Kukla
Ludovici
Mohrbacher
Ho
Miranda
Rodgers
Hitchens
Leo
Gauthier
Ho
Scott
De Clercq
Pauwels
Andries
Janssen
Janssen
4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO), 1, have been shown to significantly inhibit HIV-1 replication in vitro by interfering with the virus's reverse transcriptase enzyme. They have also demonstrated potential cl
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(1995)
