Synthesis anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1- jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 3

Article abstract of DOI:10.1021/jm00005a005

4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO), 1, have been shown to significantly inhibit HIV-1 replication in vitro by interfering with the virus's reverse transcriptase enzyme. They have also demonstrated potential cl