Asymmetric synthesis of (-)-)2E,4R,5S,11R)-cladospolide A, induced by chiral sulfoxides

Article abstract of DOI:10.1016/0957-4166(95)00040-V

An enantioselective synthesis of (-)-cladospolide in which all the chiral centers are created by asymmetric reduction of β-ketosulfoxides, is reported.