Synthesis of 2′,3′-dideoxycyclo-2′-pentenyl-3′-C-hydroxymethyl carbocyclic nucleoside analogues as potential anti-viral agents

Article abstract of DOI:10.1016/0040-4020(94)01067-A

The synthesis of optically pure unsaturated carbocyclic nucleoside analogues is described. (3,4S)-Bis(t-butyldiphenylsilyloxymethyl)-2-cyclopenten-1R and 1S-ol were coupled with 6-chloropurine and 2-amino-6-chloropurine respectively, using a modified Mits