A VERSATILE TOTAL SYNTHESIS OF EPIBATIDINE AND ANALOGS

DOI: 10.1016/0040-4039(93)88063-O

Source and publish data:

Tetrahedron Letters p. 4477 - 4480 (1993)

Update date:2022-09-26

Topics:

Authors:

Huang, Dao Fei

Shen, T. Y.

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Article abstract of DOI:10.1016/0040-4039(93)88063-O

A racemic mixture of epibatidine, a potent analgesic alkaloid possessing a 7-azanorbornane structure, has been synthesized via a versatile four-step synthetic route: a Diels-Alder reaction of N-carbomethoxy pyrrole and phenylsulfonyl 6-chloro-3-pyridyl ac

Full text of DOI:10.1016/0040-4039(93)88063-O

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