STUDIES ON TUMOR PROMOTERS: V. COMPLEMENTARY 1,4-STEREOCONTROL IN PHORBOID CYCLOHEPTENE SYNTHESIS VIA THE DIVINYLCYCLOPROPANE REARRANGEMENT

Article abstract of DOI:10.1016/S0040-4039(00)82443-0

Methodology for the synthesis of B-C ring precursors and analogs of the phorbol esters is described which allows for complementary 1,4-stereocontrol in the formation of seven-membered rings through the selective formation and rearrangement of vinyl enol cyclopropanes.